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81.
This study explores the importance of psychographic characteristics as potential segmentation bases in the higher education sector. In particular, we develop a taxonomy of university students based on their achievement orientation and prestige sensitivity. The study analyses the survey data obtained from 948 respondents using cluster analyses and multiple analysis of variance (MANOVA), indicating interesting findings. Three distinct clusters emerge, namely Strivers, Modest Achievers and Prestige-seeking Innovators. Findings reveal that Prestige-seeking Innovators have a more positive attitude towards the university, whereas Strivers have the strongest sense of regret over their decision to enrol at their current university and would seize the opportunity to enrol in a more prestigious university. The taxonomy is highly relevant to marketers of higher education institutions as it gives insights into potential bases for segmentation, positioning and communication strategies targeting the specific characteristics of each segment.  相似文献   
82.
Aims: To develop a budget impact model (BIM) for estimating the financial impact of formulary adoption and uptake of calcipotriene and betamethasone dipropionate (C/BD) foam (0.005%/0.064%) on the costs of biologics for treating moderate-to-severe psoriasis vulgaris in a hypothetical US healthcare plan with 1 million members.

Methods: This BIM incorporated epidemiologic data, market uptake assumptions, and drug utilization costs, simulating the treatment mix for patients who are candidates for biologics before (Scenario #1) and after (Scenario #2) the introduction of C/BD foam. Predicted outcomes were expressed in terms of the annual cost of treatment (COT) and the COT per member per month (PMPM).

Results: At year 1, C/BD foam had the lowest per-patient cost ($9,913) necessary to achieve a Psoriasis Area and Severity Index (PASI)-75 response compared with etanercept ($73,773), adalimumab ($92,871), infliximab ($34,048), ustekinumab ($83,975), secukinumab ($113,858), apremilast ($47,960), and ixekizumab ($62,707). Following addition of C/BD foam to the formulary, the annual COT for moderate-to-severe psoriasis would decrease by $36,112,572 (17.91%, from $201,621,219 to $165,508,647). The COT PMPM is expected to decrease by $3.00 (17.86%, from $16.80 to $13.80).

Limitations: Drug costs were based on Medi-Span reference pricing (January 21, 2016); differences in treatment costs for drug administration, laboratory monitoring, or adverse events were not accounted for. Potentially confounding were the definition of “moderate-to-severe” and the heterogeneous efficacy data. The per-patient cost for PASI-75 response at year 1 was estimated from short-term efficacy data for C/BD foam and apremilast only.

Conclusions: The introduction of C/BD foam is expected to decrease the annual COT for moderate-to-severe psoriasis treatable with biologics by $36,112,572 for a hypothetical US healthcare plan with 1 million plan members, and to lower the COT PMPM by $3.00.  相似文献   

83.
本文在总结目前国内外产业发展成本评价相关成果和地方政府相关改进政策需求的基础上,提出了对地区产业发展成本重点调整对象的确定方法和改进政策的制定思路:一是从综合成本分析入手,但更为注重不同成本因素的比较分析,即明确地区产业发展中哪些成本是短板;二是考察分析地区优势行业对不同成本因素的敏感性,即明确该行业对哪些成本较为敏感,从而确定影响产业发展的关键成本制约。根据这一思路,以北京市高端制造业为例,通过横向比较的方法具体测算出北京市综合成本的相对领先和落后环节,采用相关分析方法确定出高端制造业相对敏感的成本因素,从而明确了北京市高端制造业今后发展中需要解决的关键成本制约,并通过对北京市这些方面成本偏高的原因分析,提出了一些有针对性的政策建议。  相似文献   
84.
孙晓琳 《价值工程》2009,28(11):157-163
大量的经验文献支持了流动性假说,认为内部现金流是影响公司投资的一个重要因素。文中基于信息不对称下的融资约束理论与自由现金流的代理成本假说,回顾了关于投资现金流敏感性存在及其根源的国内外相关研究成果,梳理了该领域的研究脉络,并对主要结论进行了总结与评论。对文献研究发现,大多数研究均证实了投资与现金流之间具有较强的敏感性,但挖掘这种敏感性的根源却尚未达成一致的结论。尤其随着股权结构的引入,考虑到管理层内部持股的激励与堑壕效应、股权集中下控股股东的监督与侵占效应,该领域的研究纷繁复杂。但基于股权结构的研究是揭示这种敏感性的根源、探索非效率投资治理机制的有效途径。  相似文献   
85.
基于净现值指标的概率分析研究   总被引:1,自引:0,他引:1  
安雅琴  何松柏  杨建明 《价值工程》2009,28(11):136-138
研究了经济评价中的概率分析问题。在敏感性分析的基础上,对主要评价指标—项目净现值的概率分析引用了一种新的方法,实例表明该方法简单可行,为项目经济评价工作提供了新的思路。  相似文献   
86.
徐凤  杨桂元 《价值工程》2009,28(5):136-140
首先,对条件极值问题中资源的影子价格进行了讨论,根据数学规划的Kuhn-Tucker条件,得出条件极值问题中的影子价格也表现为边际利润(拉格朗日乘子)。然后,讨论一般非线性规划问题中资源的影子价格和影子成本,并用证券投资组合优化模型为案例对收益率的边际成本(风险)进行分析。  相似文献   
87.
The submitted paper proposes the possible use of integrated semi-quantitative risk assessment of groundwater resources. There are risks resulting from both natural and anthropogenic hazard sources. Activation of these types of hazard sources can cause damage to, or destruction of, particular hydrogeological structures and technological equipment of selected groundwater resources suitable for the emergency drinking water supply of the population. The process of risk assessment is based on the described register of hazards, including semi-quantitative assessment of the frequency with which the assessed sources of hazards are activated, the register of sensitivity together with the semi-quantitative sensitivity assessment of selected threatened elements of the assessed water resource and the determination of their criticality. The semi-quantitative risk assessment should become one of the important criteria for classifying groundwater resources which have been proposed for emergency water supply. The classification carried out on the basis of the above-mentioned principle can contribute to faster selection and effective use of groundwater resources, as well as to the enhancement of emergency and crisis planning systems when the public system is either damaged or destroyed.  相似文献   
88.
Upon differentiating the Thiele differential equations and the equivalence condition with respect to some parameter appearing in the equations, one obtains differential equations for the derivatives of the state-wise reserves and the premium level with respect to the parameter. The solution to these equations measures the impact on premiums and reserves of a change in the parameter. Typically only numerical results can be obtained, but the method applies quite generally to multi-state policies and to virtually any parameter, and so represents a panacea in (the vast majority of) situations where analytical results are out of reach. Extensions to higher order derivatives and higher order conditional moments are straightforward. A difference method for computation is devised, and numerical results are reported for some practical cases.  相似文献   
89.
服务外包产业升级是以高科技、高附加值的高端服务及研发环节转移为主要特征的全球产业结构升级的必然趋势。基于服务外包产业知识密集型的产业特点,本文从科技创新的视角,选取全国服务外包示范城市与创新城市的交叉样本作为研究对象,通过主成分分析法以及逐步回归法确定了影响服务外包产业升级的重要科技创新因素,包括企业R&D经费支出占产品销售收入比重和人均GDP,具有潜在驱动倾向的科技创新因素包括大专院校在校学生数、专业技术人员占就业人员比重、R&D经费支出与GDP比例等。在此基础上,本文通过构建回归方程,计算分析自变量的弹性灵敏度指数,根据计算结果提出应从挖掘专业人才潜力、增加科技投入强度等方面推动服务外包产业的升级。  相似文献   
90.
消费者是整个优质蔬菜产业管理过程的最终目标指向,其在优质蔬菜消费问题上所体现的态度和消费倾向会对政府和企业行为选择产生深刻影响。研究我国优质蔬菜消费者行为,对积极推进我国优质蔬菜产业快速、健康发展具有重要的理论价值和现实意义。本文在国内外研究现状和评价的基础上,另辟蹊径,从优质蔬菜消费者行为的外在表现——消费者麻木和消费者敏感入手,结合相关案例剖析了其效应,透析了影响优质蔬菜消费者行为外在表现的内在原因,并提出了相关对策。  相似文献   
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